The Science Behind Nyne
Your pill depletes. Nyne replenishes.
The first supplement designed specifically to replace the 9 nutrients your birth control takes from you.
Shop NowThe first supplement designed specifically for women on the pill
Your birth control depletes 9 essential nutrients. Every symptom — bloating, mood swings, fatigue, cravings, skin issues — is a downstream effect. Nyne replaces all 9 in one daily supplement.
Feel the Nyne Difference
De-Bloat & Fluid Balance
Magnesium restores fluid balance while LactoSpore® probiotic addresses progesterone-driven gut slowdown — the real reason you bloat on the pill.
Mood & Emotional Balance
B6 (P-5-P) is required for serotonin and dopamine production. The pill depletes it. Nyne replaces it in the active form your body can use immediately.
Sustained Energy
B12, B6, folate, riboflavin, and magnesium are all required for ATP production. When the pill depletes them, your energy crashes. Nyne puts them back.
Clearer Skin
Zinc regulates sebum production — fewer jawline breakouts. Vitamin C supports collagen. Vitamin E protects skin cells from oxidative damage.
The Research Behind Nyne
9
essential nutrients depleted by oral contraceptives (Palmery 2013)
63%
higher IBS diagnosis rate in women on the pill (Bird et al. 2012)
40%
of women carry MTHFR — folic acid doesn't work for them. Nyne uses methylfolate.
60%
less muscle mass gained by women on OCP vs non-users (Riechman/Lee 2022)
"Bought this for the bloating honestly. Didn't expect my mood to level out too. My boyfriend literally asked me what changed because I stopped snapping at him over nothing. I didn't even connect it to nyne until he said something. 10/10"
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Individual results may vary.
The Science Behind Nyne
NUTRIENT DEPLETION
How It Works
Your birth control pill depletes 9 essential nutrients — magnesium, B6, B12, folate, riboflavin, vitamin C, vitamin E, zinc, and selenium. Without these nutrients, your body can't produce serotonin, regulate fluid balance, support energy metabolism, or protect your cells.
These Effects Feel Like
How Nyne Helps
Nyne replaces all 9 depleted nutrients in their most bioavailable forms — P-5-P instead of pyridoxine, methylfolate instead of folic acid, methylcobalamin instead of cyanocobalamin. Your body can use them immediately.
Hear From Our Customers
"I was so skeptical. Another supplement promising to fix everything? But I figured $30 for a month was worth trying. It's been 5 weeks and I genuinely feel different. More energy, less bloated, my skin is clearer along my jaw."
GUT DISRUPTION
How It Works
Progesterone in your birth control relaxes smooth muscle throughout your body — including your gut. This slows peristalsis, causing food to sit longer, gas to build, and visible distension by afternoon. Women on OCPs are 63% more likely to be diagnosed with IBS.
These Effects Feel Like
How Nyne Helps
LactoSpore (Bacillus coagulans MTCC 5856) is a spore-forming probiotic clinically proven to reduce bloating (p<0.01). Combined with magnesium for gut motility support.
Hear From Our Customers
"I spent years thinking my bloating was food related. Turns out it was my birth control."
APPETITE & HORMONAL CHANGES
How It Works
Your pill depletes B6 — the nutrient required for serotonin production. Low serotonin drives carb and sugar cravings. Meanwhile, the pill suppresses free testosterone by ~61% and increases SHBG, reducing your body's ability to build lean muscle.
These Effects Feel Like
How Nyne Helps
Vitamin B6 (P-5-P) supports serotonin and dopamine production to help normalize appetite. The full B-vitamin + magnesium stack supports metabolic function.
Hear From Our Customers
"I don't know how to explain this but the sugar cravings just... stopped? Like I walked past the break room donuts yesterday and didn't even think about it. I'm on Lo Loestrin and I've been taking nyne for about a month. The scale hasn't changed much yet but I'm not gaining anymore which is the first time I can say that in 8 months"
Transparently formulated at clinically studied dosages for maximum efficacy
MEET OUR HERO INGREDIENTS:
Magnesium Glycinate
The most versatile mineral in nyne
Found in:
Depleted by hormonal birth control
Benefits:
Fluid balance (de-bloat), GABA production, ATP energy
Vitamin B6 (P-5-P)
Active form — no liver conversion needed
Found in:
Depleted by all combined OCPs
Benefits:
Serotonin + dopamine production, reduces cravings
Folate (L-5-MTHF)
Methylfolate — works for 100% of women
Found in:
Depleted by all hormonal contraceptives
Benefits:
DNA synthesis, neurotransmitter production, cell repair
Vitamin B12
Methylcobalamin — the active form
Found in:
Depleted by combined oral contraceptives
Benefits:
Energy metabolism, red blood cell formation, cognitive function
Zinc Bisglycinate
Chelated for gentle, superior absorption
Found in:
Depleted by hormonal birth control
Benefits:
Sebum regulation (skin), leptin regulation (appetite), immune support
Riboflavin (B2)
The activator — makes B6 work better
Found in:
Depleted by combined OCPs
Benefits:
Activates P-5-P, FAD cofactor for energy, cellular repair
Vitamin C
Antioxidant and collagen support
Found in:
Depleted by hormonal birth control
Benefits:
Collagen synthesis (skin), immune support, antioxidant
Vitamin E
Natural d-alpha form — 2x bioavailability
Found in:
Depleted by combined oral contraceptives
Benefits:
Cell membrane protection, skin health, antioxidant defense
Selenium
L-Selenomethionine — 90%+ absorption
Found in:
Depleted by hormonal contraceptives
Benefits:
Thyroid protection, glutathione production, immune function
Vitamin D3
Commonly deficient in young women
Found in:
Not BC-depleted, but most women are low
Benefits:
Mood support, immune function, bone health
LactoSpore Probiotic
Clinically proven spore-forming probiotic
Found in:
Added for BC-driven gut disruption
Benefits:
Reduces bloating (p<0.01), shelf-stable, survives stomach acid
OBGYN
Dr. Elevyn Reed
As a women's health specialist, I'm impressed by how thoughtfully this formula addresses the specific nutrient gaps created by hormonal contraceptives. The bioavailable forms and targeted dosages show a deep understanding of the science.
🩺 Clinicians' Choice 🩺
887 clinicians share Nyne on FrontrowMD without compensation.
View clinicians & learn more
nyne — Birth Control Companion
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Ingredients
Our formula contains a carefully selected blend of vitamins, minerals, and botanical extracts designed to support your body while on hormonal birth control.
How to Take
Take 2 capsules daily with food. For best results, take consistently at the same time each day.
Nyne makes ending BC side effects easy, safe, and affordable.
If you purchased premium versions of all the quality ingredients in Nyne independently — it would look something like this:
Buy each ingredient
$224.60
Why We Built Nyne
What to Expect with nyne
Your body didn't get depleted overnight. Nyne rebuilds your nutrient levels steadily — here's the timeline most women experience.*
*Based on published nutrient repletion research and early customer feedback.
Week 1–2
Your body starts absorbing and rebuilding depleted nutrient levels. B vitamins and magnesium begin replenishing. You may not feel dramatic changes yet — this is your foundation phase.*
Week 3–4
Most women notice bloating and energy changes first. Magnesium restores fluid balance, B12 and B6 support energy production. Mood improvements often follow as serotonin pathways rebuild.*
Month 2
Full benefits are building. Bloating is noticeably reduced. Energy is more sustained. Cravings may be less intense as B6 supports serotonin and zinc regulates leptin.*
Month 3+
Nutrient levels are more fully restored. Skin clarity improves as zinc normalizes sebum. This is when most women say they "feel like themselves again."*
*Individual results may vary. These statements have not been evaluated by the FDA.
Frequently Asked Questions
Have a question that's not here? Reach out to support@trynyne.com
Does Nyne interfere with my birth control?
No. Nyne was specifically designed to be safe with hormonal birth control. We deliberately excluded every ingredient known to interfere — DIM, Vitex, St. John's Wort, BioPerine, Inositol, and Berberine are never in our formula. Works with the pill, patch, ring, hormonal IUD, implant, and shot.
How does Nyne work?
Research shows hormonal birth control depletes 9 essential nutrients from your body. Nyne replaces all 9 in bioavailable forms your body can use immediately, plus adds Vitamin D3 and a clinically-proven probiotic for gut health.
Is Nyne 3rd party tested?
Yes. Every batch is independently tested for active ingredient potency, microbial contamination, heavy metals, and pesticides. We publish our test results on our website.
What can I expect to notice?
Most women notice bloating and energy changes within 2-4 weeks. Mood improvements follow by weeks 3-4. Full benefits build over 60-90 days as nutrient levels replenish.
I already take a multivitamin — do I need Nyne?
A generic multivitamin isn't designed for women on birth control. It has the wrong forms (folic acid vs methylfolate, pyridoxine vs P-5-P), wrong doses, and no targeted probiotic. Nyne replaces your multi with something purpose-built.
How long until I see results?
Your body didn't get depleted overnight — it takes time to replenish. Week 1-2: foundation building. Week 3-4: most women notice bloating and energy changes. Month 2+: full benefits. Consistency is key.
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